Video Transcripts

Prostate Cancer Videos

Prostate Cancer Treatment Research Foundation Video Transcripts

The Foundation has included the transcripts for all videos to assist in your understanding of each topic. If you wish to submit a translated version of a transcript, we will consider adding the translated version to the video as subtitles. Thank you in advance for your assistance.

Video Title: Prostate Cancer Treatment Research Foundation

Prostate Cancer Treatment Research Foundation.
Increasing Knowledge – Building Hope.

Welcome to the Prostate Cancer Treatment Research Foundation. We represent a team of Doctors from around the globe, here to help you make your treatment decision.

Following thousands of patients for years after treatment, we’ve compiled a study to help you compare the effectiveness of different treatments. The Foundation has condensed this information into an understandable format to walk you through comparing treatments. Our goal is to help you make the best possible treatment decision.

Select COMPARE TREATMENTS to see how.

Prostate Cancer Treatment Research Foundation www.pctrf.org

Video Title: Find the Best Prostate Cancer Treatment

Prostate Cancer Treatment Research Foundation.
Increasing Knowledge – Building Hope.
Dr Peter Grimm, Prostate Cancer Results Study Group.

Doctor Peter Grimm is the Executive Director of the Prostate Cancer Center of Seattle. For almost 30 years Doctor Grimm has worked tirelessly in the battle against prostate cancer treating thousands of patients and training even more physicians.

You have prostate cancer. The good news is that the overall survival for prostate cancer is generally very good. The next question, however, is which treatment is best for you? Which treatment will result in the long term likelihood that the cancer will never return. In order to make this decision you need current, up to date, unbiased information.

Doctor Peter Grimm is the leader of the Prostate Cancer Results Study Group. A group of physicians from around the world, who have come together to review the worlds literature on the effectiveness of different prostate cancer treatments.

The Prostate Cancer Results Study Group has reviewed more than 28,000 articles, published from all available respected journals. From these articles, over 1100 were identified as related to treatment results. Spanning a fourteen year period, these results provide a roadmap of which prostate cancer treatments have been the most successful in keeping cancer from coming back. This work is the focus of this video.

The Prostate Cancer Results Study Group work is unprecedented. It represents fourteen years of evaluating the results of the various treatments that are available for your cancer. With this information you can compare treatments, you can compare combination of treatments and determine which treatments are best for you. It will help you determine which treatment will result in the cancer going away and never coming back in your lifetime.

Fred Owen is Executive Director of the Prostate Cancer Treatment Research Foundation. Fred is leading the effort to share information of the effectiveness of different prostate cancer treatments, through the Foundation website.

The Prostate Cancer Treatment Research Foundation has recently made the results of this study easily available through an interactive website. To use this new comparison tool, you’ll need to know three things about your diagnosis.

Your PSA level, the Stage of your cancer and the Grade or Gleason Score from the biopsy. Using these numbers the website will help determine your risk group, Low, Intermediate or High Risk. The interactive chart on the website allows you to compare the effectiveness of each treatment. For example, using the chart for high-risk disease you can see the results for surgery.

The scale on the left to the chart shows the percentage of patients with no sign of cancer recurrance. The scale at the bottom shows how these results change over the years. To compare other treatments simply select them in the list. Here we compare surgery with external beam radiation. In the high-risk categories you can also view the results of combined treatments, such as External Beam Radiation, Seed Implants and ADT or Hormone Therapy.

Making this information directly available to you as opposed to the medical community only, is remarkable. This information is available through the Foundation website and can be used along with your physician and your family to help you make an informed decision about which treatment might be best for you.

The Prostate Cancer Treatment Research Foundation is working to share information on the effectiveness of the different prostate cancer treatments for patients so they can make an informed decision on the best treatment plan.

For more information please visit our website at www.pctrf.org and click on compare treatments. This work can only continue with the help of people like you. We appreciate your comments and support.

Prostate Cancer Treatment Research Foundation. www.pctrf.org

Video Title: Prostate Cancer Treatment Options – Comparison Tutorial

Prostate Cancer Treatment Research Foundation.
Increasing Knowledge – Building Hope.

The treatments on this chart are Surgery, External Beam Radiation, Seeds or Brachytherapy, the combined treatment of Brachytherapy and External Beam Radiation, Proton Radiation, High Dose Rate Radiation and High Intensity Focused Ultrasound. Note that High Dose Rate Radiation and High Intensity Focused Ultrasound do not have enough data points to make up an Ellipse, but the data is included for completeness.

To understand more about Low Risk Prostate Cancer and the Treatment options, select the Low Risk Commentary. Here you will find a description of the disease and a overview of the options for Low Risk Patients.

To view the results of a treatment, select the square next to the treatment name. For example, selecting surgery causes a series of dots and squares to appear on the page, along with an Ellipse. Each dot or square represents a study with a different number of patients. To learn more about a particular study, hover over the dot. If you click on the dot, a link will appear that will take you to an abstract of the study.

To see the entire list of referenced articles on this page, click on the Low Risk Article Reference link. Here you will find a link to all the studies, covering the patients, used to create the Low Risk Chart. The scale on the left side of the graph is Percent of PSA Progression Free. Measuring PSA Progression Free , as opposed to survival, is a true indicator of the success of the Treatment. A PSA Progression Free of 100% implies that the cancer has not returned, and no follow up treatment was necessary.

The bottom of the graph tracks time in years, in this case up to 16 years. The longer a Treatment can maintain a PSA Progression Free close to 100%, the more effective the Treatment. The treatment ellipse is mathematically calculated to help you visualize how the patients are doing with the selected treatment. The mid point of the ellipse shows on average how the patients responded to a that treatment. The direction of the ellipse, shows how the patients trended over time. To learn more about the process behind creating the ellipse’s, just click on How the Charts Work.

If you choose to focus your study on just one treatment, you can de-select the others on the chart. This capability also works within the key. You can change the data presented, by selecting or de-selecting them in the key. In the case of surgery, there are two types of surgery represented by the ellipse, radical prostatectomy and robotic surgery. Using the key, you can focus in on one or both, by viewing just the data points.

If you are unfamiliar or would like to understand more about a treatment, click on the treatment name and the Treatment Description page will appear. Here you will find descriptions of all the treatments being compared on the graph.

In the upper right hand corner of the chart are the options to Print or Download the current page, reflecting the treatments you have currently selected.

Prostate Cancer Treatment Research Foundation. www.pctrf.org

Video Title: Advice for Patients with Prostate

Prostate Cancer Treatment Research Foundation.
Increasing Knowledge – Building Hope.
Edward Weber, M.D. Medical Oncologist, Prostate Cancer Results Study Group.

You’ve been diagnosed with prostate cancer. If your diagnosis came as a result of a schedule of appropriate PSA testing, it’s very likely the disease has been found early. This comes as a surprise to most men and they are quite anxious at this point. Being told you have prostate cancer is a frighting message carrying a heavy baggage The normal urge is to plunge into a “crash course” to learn how to manage this unwelcome intrusion into your life, a crash course that you are unlikely to know how to handle objectively.

So … what to do? 

Stop, take a deep breath, step back a bit, and think carefully. It is extremely unusual that there is any need to rush to a decision. Most cancers have been sitting quietly in your prostate and growing for 10 to 15 years, with the most aggressive ones developing over 10 or so years. So … you haven’t just “gotten” prostate cancer. You just have been “diagnosed” with a cancer that you have been living with for a long time.

Likely your diagnosis has been made by a biopsy performed by a urologist, an expert in the surgical management of prostate cancer. It’s extremely important for you to know that any cancer, low grade, intermediate, or high grade can be successfully treated with surgery, augmented if need be by radiation, external beam radiation therapy, permanent radioactive seed placement, for example brachytherapy, combined if indicated by external radiation, and proton therapy. In some cases cryotherapy or short course of focused radiation with Cyberknife technology is chosen.  Active surveillance is a very important option for management of low-risk cancer. It warrants serious consideration and discussion.

Take your time and learn about the treatment options available to you. You may want to consider several of these. In most situations, all of these are reasonable options. But for some men their individual  situations makes a particular option the better choice. Nor do all options suit every man’s emotional reaction to the diagnosis or his preferences. 

So what should you do?

You do not need to become an instant expert. Instead, you need to have consultations with possibly several specialists who can describe their treatments and help you decide which treatment fits you best. In the process you may well have consultations with a urological surgeon and possibly several radiation therapists each skilled in a special type of radiation therapy. If your disease is more complex, you may want an option from medical oncologist, which is what I am.

It’s important to be informed, but you don’t need to do this alone. That’s what the specialists are there for. This is the time for deliberation, since once treated you cannot reverse the course.

After stopping, and thinking, and gaining expert guidance, then take action. Most not all of the mental fuzz of anxiety and consternation will subside. But when you have made a considered decision you will feel very comfortable. 

Then you can devote your energy to the goal of successful treatment and recovery. The outcome of therapy for this disease is generally excellent, very likely much better than you might have thought. With careful deliberation on your part and treatment by experts, your will be able to make this usual good outcome your outcome.

Prostate Cancer Treatment Research Foundation. www.pctrf.org

Video Title: Reduce Prostate Cancer Radiation Side Effects

Prostate Cancer Treatment Research Foundation,
Increasing Knowledge – Building Hope.
R. Alex Hsi, M.D. Radiation Oncologist.

Radiation treatment for prostate cancer can create unwanted side effects. I’d like to show you a revolutionary new technology called SpaceOAR hydrogel. This product dramatically reduces the effects of radiation on normal rectal tissue adjacent to the prostate during radiation treatments for prostate cancer.

The challenge in treating prostate cancer with radiation therapy is that the prostate and rectum sit directly next to each other, so the rectum inevitably receives unwanted radiation. So a conceptually simple yet ingenious solution is to place a water based gel in between the prostate and rectum to create a space, or buffer zone, that pushes the rectum out of the way while the prostate is being treated with radiation.

SpaceOAR hydrogel can increase the natural space between the prostate and rectum from 2 mm to over a centimeter. In a large randomized trial carried out in the US, we found that placement of the gel resulted in a 75% reduction in high dose radiation to the rectum which then translated into a 70% reduction in clinical rectal side effects.

Prostate Cancer Treatment Research Foundation. www.pctrf.org

Video Title: Is PSA Testing Necessary ?

Prostate Cancer Treatment Research Foundation.
Increasing Knowledge – Building Hope.
Edward Weber, M.D. Medical Oncologist, Prostate Cancer Results Study Group.

So… is getting a simple blood test for your PSA no longer necessary? A Federal government agency called The United States Preventive Service Task Force thought so when in 2012 it recommended no more screening with the PSA test. The consequences of this misguided recommendation are already being seen. More men are being diagnosed with advanced prostate cancer. Following their recommendation could greatly shorten your hope for a long life. A late diagnosis of prostate cancer, a cancer diagnosis after it has already spread, is a cancer that is not curable, and is a killer.

Early awareness of your PSA value gives you the best chance for cure, or at least a shot at controlling the disease and bypassing very unwanted symptoms. Most people do not need yearly testing, but each man should have a baseline test starting at age 45, or a first test at any age, to see where he stands with this disease. Further testing can then be individualized based on that first result. Maybe you will never need another test, or maybe a test only every five years or so. So get tested. Your family will be proud of you and you will be glad you did.

Prostate Cancer Treatment Research Foundation. www.pctrf.org

Video Title: PSA Prostate Specific Antigen

Prostate Cancer Treatment Research Foundation.
Increasing Knowledge – Building Hope.
Dr. Peter Grimm, Prostate Cancer Results Study Group

PSA or Prostate Specific Antigen is a protein found in prostate cells and blood of normal men. Prostate cancer and benign prostate conditions can result an elevation of the PSA, resulting in the need for further evaluation by your physician. The PSA test is our most sensitive test and most effective test for the early detection of prostate cancer.

After any treatment, the PSA can be used to determine whether the treatment has been successful. A rise in the PSA, following treatment, can indicate that the treatment has failed, resulting in the need for further diagnostic tests and possible for treatment.

At the Foundation we use the PSA test to compare the various treatments. This is called the PSA Progression Free. PSA Progression Free simply means that the PSA has dropped to a very low level, has not risen, has not progressed, over the lifetime of the patient. A successful prostate cancer treatment is therefore one which the PSA has not progressed, has not risen, over the lifetime of the patient.

We encourage patients to evaluate the results and compare the results of the various treatments for prostate cancer. By doing so, patients can understand which treatment will result in the cancer going away and never returning in their lifetime.

We have analyzed the prostate cancer treatments for thousands of patients and made this current up to date information available to you, such that you can make a good decision regarding which treatment will result in the cancer never returning in your lifetime.

Prostate Cancer Treatment Research Foundation. www.pctrf.org

Please visit our website at www.pctrf.org

Video Title: Prostate Cancer Treatment Research Foundation Trailer

Prostate Cancer Treatment Research Foundation.
Increasing Knowledge – Building Hope
Dr. Peter Grimm, Prostate Cancer Results Study Group

You have Prostate Cancer.

Prostate Cancer? How bad is it? Can it be treated? Can it be cured?

Which treatment will result in the cancer going away and never coming back in your lifetime?

What are the Options? Surgery? Brachytherapy? External Beam? Cryosurgery? Ultrasound?

Using these numbers website will help determine your risk group, low, intermediate or high risk?

Which prostate cancer treatments have been the most successful in keeping cancer from coming back?

Treatments Compared. World-wide team of doctors. Reviewed thousands of studies. Tracked patient results for years.

Reviewed studies covering 83,565 patients, some for as long as 15 years.

Here we compare surgery with external beam radiation.

www.pctrf.org. Interactive web site. See treatment results. Find the best treatment.

Watch the video in as many as 60 different languages.

The Prostate Cancer Results Study Group work is unprecedented.

Prostate Cancer Treatment Research Foundation. www.pctrf.org

Video Title: Find the Best Prostate Cancer Treatment For You

Prostate Cancer Treatment Research Foundation
Increasing Knowledge – Building Hope

PROSTATE CANCER ?

PROSTATE CANCER ?
How bad is it? Can it be treated? Can it be cured?

What are the OPTIONS ?

What are the OPTIONS ?
Surgery? Brachytherapy? External Beam? Cryosurgery? Ultrasound?

Which TREATMENT ?

Which TREATMENT ?
Has a chance for a cure? Stops the spread of cancer? Will be best for me?

Treatments COMPARED

Treatments COMPARED
World-wide team of doctors. Reviewed thousands of studies. Tracked patient results for years.

www.pctrf.org

www.pctrf.org
Interactive web site. See treatment results. Find the best treatment for YOU.

Prostate Cancer Treatment Research Foundation www.pctrf.org

Video Title: Video Translation Help

Prostate Cancer Treatment Research Foundation
Increasing Knowledge – Building Hope.

The Prostate Cancer Treatment Research Foundation
Videos are enabled with Closed Captions. This allows the viewer to take advantage of Google Translate, and watch the video in as many as 60 different languages.

Google translate is not perfect, but we hope this will allow you to understand the intent of the video. To enable closed captions, click on the SUBTITLES or CC icon on the video control bar. This will enable closed captions in English.

If you wish to translate the subtitles or closed captions to another language, first click on the SETTINGS icon, also on the video control bar. A popup menu will appear. Click the DOWN ARROW next to the default language of English.

Then select TRANSLATE CAPTIONS.

Another pop up Menu will appear Entitled TRANSLATE. Select the DOWN ARROW and scroll to find your language. In this example I have selected Traditional Chinese. Then press OK.

If you prefer another language, use the setting key to select French, or German, or Spanish, or the language works best for you.

Prostate Cancer Treatment Research Foundation www.pctrf.org